Title page :
The title page should list the title of the article and the full names and institutional affiliations of all authors, a short running title of less than 40 characters including spaces, and the contact information for correspondence, including name, academic degree(s), address (institutional affiliation, city, zip code, and country), telephone and fax numbers, and e-mail address.

Abstract and Keywords :
The abstract of the original article should be no more than 250 words and be divided into four subsections: Background/Aims, Methods, Results, and Conclusions. Abbreviations, if needed, should be kept to an absolute minimum and identified clearly. Up to five keywords should be listed below the abstract. For selecting keywords, refer to the Index Medicus Medical Subject Headings [7].

Introduction :
The introduction should include a brief background of the topic for general readers and should refer to the most pertinent papers and relevant findings of others in the field. The specific questions to be addressed by the study should also be described.

Methods :
Methods should be described concisely, but in sufficient detail to allow other qualified investigators to repeat the experiments. The sources of special chemicals or reagents should be given along with the source location (name of company, city, state/province, and country). If needed, include information on the institutional review board/ethics committee approval or waiver and informed consent. Methods of statistical analysis and criteria for statistical significance should be described.

Results :
The results should be presented in logical order using text, tables, and illustrations. Duplication of table or figure content should be avoided.

Discussion :
The discussion section is a concise interpretation and discussion of the data and results. Speculation is permitted, but it must be supported by the presented data. Content already presented in the results should not be repeated in the discussion.

Acknowledgments :
All persons who have made substantial contributions, but who have not met the criteria for authorship, are acknowledged here. All sources of funding applicable to the study should be stated here explicitly.

References :
In the text, references should be cited with Arabic numerals in brackets, numbered in the order cited. In the references section, the references should be numbered and listed in order of appearance in the text. List all authors if there are less than or equal to six authors. List the first three authors followed by “et al.” if there are more than six authors. If an article has been published online, but has not yet been given an issue or pages, the digital object identifier (DOI) should be supplied. Journal titles should be abbreviated in the style used in Index Medicus. Other types of references not described below should follow The NLM Style Guide for Authors, Editors, and Publishers[8].


Tables :
Tables should be constructed simply and should not duplicate information found in the figures. Each table should have a title, begin on a new page, and be numbered with an Arabic numeral in the order of its citation in the text. If numerical measurements are given, the unit of measurement should be included in the column heading. The statistical significance of observed differences in the data should be indicated by the appropriate statistical analysis. All nonstandard abbreviations should be defined in footnotes. Lower case letters in superscripts ^{a), b), c) ...} should be used for special remarks.

Figures :
Only high-resolution figure files (preferably 600 dpi for color figures and 1200 dpi for line art and graphs) should be submitted. Figure images should be provided in EPS or TIF format, although the JPEG format is allowed for color figures. The smallest parts of a figure should be legible when they are reduced to the final print size. Each figure should be saved as a separate electronic file. Symbols, arrows, or letters used in photographs should contrast from the background visually. The legend for each light microscopic image should indicate the stain used and the level of magnification. Electron micrographs should have an internal magnification scale marker. All types of figures may be reduced, enlarged, or trimmed for publication by the editor.